DNA Binding Motif

						

			
Accessions: MEIS1_DRGX_1 (HumanTF2 1.0)

			
Names: MEIS1_DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: tGACrstaATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    215    196    113    941      t
02    104     28    941     37      G
03    941     35    167    226      A
04     16    941      0     27      C
05    941     67    408     96      r
06     44    585    355    272      s
07    242    151    108    941      t
08    941    142    211    243      a
09    941     36     27     40      A
10     97    139    129    941      T
11    200    114    180    760      t
12    414    218    527    239      r
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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