DNA Binding Motif

						

			
Accessions: ETV5_HOXB13 (HumanTF2 1.0)

			
Names: ETV5_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: rsCGGAwGYmrTwAa
Weblogo: 
PSSM: P0      A      C      G      T
01   1092    197    849    343      r
02    377    954    971    179      s
03    305   2481    124      0      C
04      0      0   2481      0      G
05      1      0   2481     97      G
06   2481      2      0    128      A
07   1417    135      6    923      w
08    474     50   2481      0      G
09    103    655      9   1714      Y
10    834    751    370    525      m
11    789    117   1385    190      r
12    365    120    429   2481      T
13   1576    111    209    905      w
14   2481    229    277    423      A
15   2481    737    544    547      a
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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