DNA Binding Motif

						

			
Accessions: MEIS1_EOMES (HumanTF2 1.0)

			
Names: MEIS1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: asgTGwkGaCAk
Weblogo: 
PSSM: P0      A      C      G      T
01    243     75    124    145      a
02    208    252    243    176      s
03     31     33    243     56      g
04      7     68      6    243      T
05      7      6    243     10      G
06    228     89    172    243      w
07      2     52    105    243      k
08     21      5    243     19      G
09    243      5     56     73      a
10     12    243     11     10      C
11    243     10     68     25      A
12     42     45     80     76      k
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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