DNA Binding Motif

						

			
Accessions: TFAP2C_DLX3_1 (HumanTF2 1.0)

			
Names: TFAP2C_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: yssCysvrGGCaygggssTAATkr
Weblogo: 
PSSM: P0      A      C      G      T
01    241    341    219    315      y
02    173    407    709     93      s
03     50   1116    474      7      s
04      4   1116      3    138      C
05     61    503    156    395      y
06    238    313    292    273      s
07    330    315    382     89      v
08    550     26    566     29      r
09      3     10   1116      0      G
10     78    296   1116     31      G
11      9   1116    193    280      C
12   1116    335    601    477      a
13    264    299    147    406      y
14    270    252    354    239      g
15    199    239    422    255      g
16    275    240    366    234      g
17    195    284    408    229      s
18    267    310    303    236      s
19     85    203     74   1116      T
20   1116    100    143     85      A
21   1116      0     40     76      A
22    109     53    130   1116      T
23    150    203    412    704      k
24    576    120    539     87      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TFAP2C_TF1 (Transcription factor AP-2)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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