DNA Binding Motif

						

			
Accessions: TFAP2C_MAX_2 (HumanTF2 1.0)

			
Names: TFAP2C_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: trsCCysrGGssrwrCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   7926   8385   6258  16381      t
02   4405   3643   5411   2921      r
03    761   6343  10038    579      s
04    116  16381   1530    143      C
05     56  16381     11   2236      C
06    482   5972   2670   7257      y
07   1563   6293   5869   2656      s
08   7643   3025   5156    556      r
09   3993    703  16381    158      G
10     96     53  16381     77      G
11    413  10092   6289    606      s
12   3394   5811   4433   2744      s
13   5875   2811   4469   3226      r
14   5976   2379   2689   5336      w
15   6621   2490   5472   1798      r
16    194  16381     68    108      C
17  16381    143    259     34      A
18     39  16381     62    377      C
19    369     32  16381      4      G
20     37    423    295  16381      T
21    129    132  16381     53      G
22   2860   5450   4990   3082      s
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP2C_TF1 (Transcription factor AP-2)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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