DNA Binding Motif

Accessions: ELK1_HOXB13_2 (HumanTF2 1.0)
Names: ELK1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rvCGGAArywrTwAaa
Weblogo:
PSSM: P0 A C G T
01 285 69 204 119 r
02 154 155 144 36 v
03 159 489 44 12 C
04 15 3 489 5 G
05 18 0 489 36 G
06 489 9 0 25 A
07 489 73 17 111 A
08 182 62 219 25 r
09 60 220 35 268 y
10 201 95 64 129 w
11 327 46 161 78 r
12 87 10 46 489 T
13 298 19 36 191 w
14 489 17 46 107 A
15 489 79 51 109 a
16 181 111 87 108 a
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
ELK1_TF1 (Ets-domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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