DNA Binding Motif

Accessions: HOXB2_HOXB13_2 (HumanTF2 1.0)
Names: HOXB2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: cTCrTAAAatyA
Weblogo:
PSSM: P0 A C G T
01 80 256 39 6 c
02 21 47 21 292 T
03 62 381 2 60 C
04 222 6 381 0 r
05 6 0 0 381 T
06 381 15 46 79 A
07 381 38 7 37 A
08 381 81 0 1 A
09 381 97 91 12 a
10 55 110 24 381 t
11 20 232 98 381 y
12 381 29 80 5 A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB2_TF1 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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