DNA Binding Motif

						

			
Accessions: ELK1_SREBF2_2 (HumanTF2 1.0)

			
Names: ELK1_SREBF2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rtCrCGTGACCGGAAGy
Weblogo: 
PSSM: P0      A      C      G      T
01    437     91    350     40      r
02    155     81     64    632      t
03     15    787     41     15      C
04    787      2    330     58      r
05      6    787    138     65      C
06     28    141    787      6      G
07     42    117     31    787      T
08     67     35    787     48      G
09    763     11     10      3      A
10     16    687     56     28      C
11     94    787     61     71      C
12      0      0    787      2      G
13     22     36    787      1      G
14    787     16     30      6      A
15    787     17      0    156      A
16    136     69    571     11      G
17    138    204     70    375      y
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
SREBF2_TF2 (Helix-loop-helix DNA-binding domain)
ELK1_TF1 (Ets-domain)
SREBF2_TF1 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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