DNA Binding Motif

						

			
Accessions: ELK1_HOXA3_2 (HumanTF2 1.0), UN0498.1 (JASPAR 2024)

			
Names: ELK1_HOXA3, ELK1::HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 12
Consensus: rcCGGwAAtkr-
Weblogo: 
PSSM: P0      A      C      G      T
01   1044    334   1079    500      r
02    321   1496    627    155      c
03    361   2123     55    272      C
04    107    103   2123     79      G
05    145    340   2123    224      G
06   4576     59     60   2123      w
07   2123      0    183      6      A
08   2123     11    179      0      A
09    180    560    364   2123      t
10    131    311    923   1199      k
11    884    134   1239    469      r
12      0      0      0      0      -
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ELK1_TF1 (Ets-domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
P19419
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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