DNA Binding Motif

Accessions: ERF_DLX3_2 (HumanTF2 1.0)
Names: ERF_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rccGGAwrkvsyaaTta
Weblogo:
PSSM: P0 A C G T
01 115 53 72 43 r
02 34 140 47 21 c
03 53 188 29 15 c
04 2 0 188 0 G
05 3 8 188 21 G
06 188 8 1 13 A
07 188 21 3 99 w
08 62 32 78 15 r
09 21 42 51 73 k
10 59 51 64 14 v
11 26 59 80 22 s
12 31 112 31 75 y
13 188 70 84 10 a
14 188 51 39 67 a
15 0 15 12 188 T
16 32 47 32 188 t
17 188 28 70 77 a
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ERF_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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