Transcription Factor
| Accessions: | ERF_TF1 (HumanTF2 1.0) |
| Names: | Activating enhancer-binding protein 2 gamma, AP2-gamma, AP2C_HUMAN, ERF, Transcription factor AP-2 gamma, Transcription factor ERF-1 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF2 1.0 1 1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
| Uniprot: | Q92754 |
| Notes: | Ensembl ID: ENSG00000105722; Construct type: TF1(SBP); TF family: ETS; Clone source: Jolma et al. 2013 |
| Length: | 130 |
| Pfam Domains: | 23-105 Ets-domain |
| Sequence: (in bold interface residues) | 1 MADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDPDEV 60 61 ARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFIDVGL 120 121 AGGAVPQSAP |
| Interface Residues: | 21, 76, 77, 79, 80, 81, 83, 84, 98 |
| 3D-footprint Homologues: | 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B |
| Binding Motifs: | ERF_CEBPD rsmGGAwrTTGCGyAAy ERF_CLOCK CACGTGkyyGrsmGGAArym ERF_DLX2_1 rsmGGAwrtsrvymaTTA ERF_DLX2_2 rsmGGAwrtsrvymaTTa ERF_DLX3_1 avmGGAwryrgsyamTtr ERF_DLX3_2 rccGGAwrkvsyaaTta ERF_EOMES_1 rgGTGtgrvvdhrdwwtvdCACmGGAArb ERF_EOMES_2 waTmrCACMGGAwry ERF_ETV7 rsmGGAmGGAykTCCkss ERF_FIGLA rcCGGAwrCAssTGky ERF_FOXI1_1 rcCGGAwGTtkwy ERF_FOXI1_2 rtaaACmGGAArtr ERF_FOXI1_2_3 trTtkmCGGAart ERF_FOXO1 rwmAACAGGAArks ERF_HES7_1 rCCGGAAgygcGrCACGyGsc ERF_HES7_2 kkCACGyGCysacCGGAaGt ERF_HES7_2_3 gvCACGTGgyrkmsCGGAAry ERF_HOXA3 asCGGAwryrrargymaTTA ERF_HOXB13 rccGGAaryhrTwAaa ERF_MAX aCCGGAAaCACGTGs ERF_NHLH1 aGCAGCTGCCGGAWrym ERF_ONECUT2 rCCGGAArtgcsgATCGATy ERF_PITX1_1 rccGGAwGydgrgmTta ERF_PITX1_2 kscGGAwryrrkggmTta ERF_SREBF2_1 rTCACGTGACmGGAAgkr ERF_SREBF2_2 ssCGGAArTCACGTGAy ERF_TBX21_1 agGTGtgaagwrvkgktcaCrCCGGAArw ERF_TBX21_2 TmaCACCGGAAr |
| Publications: | Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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