DNA Binding Motif

Accessions: FOXJ2_HOXB13_1 (HumanTF2 1.0)
Names: FOXJ2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: tTTwAykdgwmAACA
Weblogo:
PSSM: P0 A C G T
01 26 37 53 165 t
02 12 10 18 281 T
03 33 0 0 281 T
04 118 24 5 281 w
05 281 0 37 36 A
06 56 126 0 281 y
07 47 42 104 88 k
08 148 0 133 98 d
09 36 25 186 34 g
10 163 71 114 281 w
11 173 108 11 21 m
12 281 12 27 54 A
13 281 0 40 0 A
14 10 281 1 93 C
15 281 1 46 75 A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
FOXJ2_TF1 (Fork head domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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