DNA Binding Motif

Accessions: UP00523A_1 (UniPROBE 20160601)
Names: FoxN5, FOXR1
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: scctcdmrCAAACAahyawkrk
Weblogo:
PSSM: P0 A C G T
01 0.20 0.27 0.35 0.18 s
02 0.21 0.58 0.09 0.12 c
03 0.19 0.39 0.24 0.17 c
04 0.23 0.24 0.19 0.34 t
05 0.16 0.40 0.21 0.23 c
06 0.32 0.06 0.32 0.30 d
07 0.38 0.30 0.24 0.08 m
08 0.36 0.06 0.35 0.23 r
09 0.01 0.96 0 0.02 C
10 0.98 0.01 0.01 0 A
11 0.98 0.01 0.01 0.01 A
12 0.96 0 0.01 0.03 A
13 0 0.95 0 0.04 C
14 0.92 0.01 0.05 0.02 A
15 0.51 0.20 0.18 0.11 a
16 0.33 0.26 0.07 0.33 h
17 0.16 0.40 0.05 0.39 y
18 0.36 0.22 0.22 0.20 a
19 0.30 0.09 0.24 0.38 w
20 0.11 0.24 0.27 0.38 k
21 0.28 0.16 0.44 0.11 r
22 0.21 0.16 0.26 0.37 k
Binding TFs: UP00523A (Fork head domain)
Binding Sites: AACAAACA
ACAAACAA
ATTGTTTG
CAAACAAA
CAAACAAC
GCAAACAA
AAGTTTGC
ACAAACAC
ACAAACAG
AGCAAACA
AGGCAAAC
AGTGTTTG
ATCAAACA
ATGTTTGC
CACAAACA
CGCAAACA
GACAAACA
GGCAAACA
GTCAAACA
TCAAACAA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]

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