Transcription Factor
| Accessions: | UP00523A (UniPROBE 20160601) |
| Names: | FoxN5, FOXR1 |
| Organisms: | Homo sapiens |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 135 |
| Pfam Domains: | 16-108 Fork head domain |
| Sequence: (in bold interface residues) | 1 RRLRQASSQAGRLWSRPPLNYFHLIALALRNSSPCGLNVQQIYSFTRKHFPFFRTAPEGW 60 61 KNTVRHNLCFRDSFEKVPVSMQGGASTRPRSCLWKLTEEGHRRFAEEARALASTRLESIQ 120 121 QCMSQPDVMPFLFDL |
| Interface Residues: | 56, 59, 61, 62, 63, 65, 66, 67, 69, 70, 88, 90 |
| 3D-footprint Homologues: | 3l2c_A, 7vox_H, 2hdc_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 3qrf_G |
| Binding Motifs: | UP00523A_1 scctcdmrCAAACAahyawkrk UP00523A_2 cmymvykArGACGCCAavwgasg |
| Binding Sites: | AACAAACA ACAAACAA ATTGTTTG CAAACAAA CAAACAAC GCAAACAA AAGTTTGC ACAAACAC ACAAACAG AGCAAACA AGGCAAAC AGTGTTTG ATCAAACA ATGTTTGC CACAAACA CGCAAACA GACAAACA GGCAAACA GTCAAACA TCAAACAA |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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