DNA Binding Motif

						

			
Accessions: UP00501A_3 (UniPROBE 20160601), UP00501A_4 (UniPROBE 20160601)

			
Names: P. miniata Tbrain (T-box transcription factor), PmTbr_rep1
Organisms: Patiria miniata
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: mrwmhsCsAGGTGACAtawstsv
Weblogo: 
PSSM: P0      A      C      G      T
01   0.35   0.33   0.17   0.16      m
02   0.68   0.03   0.28   0.02      r
03   0.45   0.07   0.08   0.40      w
04   0.48   0.28   0.09   0.16      m
05   0.34   0.28   0.13   0.25      h
06   0.10   0.52   0.32   0.07      s
07   0.03   0.80   0.12   0.05      C
08   0.07   0.49   0.27   0.18      s
09   0.93   0.01   0.04   0.03      A
10   0.03   0.02   0.92   0.03      G
11      0   0.01   0.97   0.02      G
12      0   0.01      0   0.98      T
13   0.01   0.01   0.98      0      G
14   0.80   0.02   0.14   0.04      A
15   0.04   0.93   0.01   0.02      C
16   0.85      0   0.13   0.02      A
17   0.19   0.22   0.17   0.42      t
18   0.49   0.09   0.23   0.18      a
19   0.36   0.08   0.22   0.34      w
20   0.04   0.52   0.28   0.17      s
21   0.18   0.12   0.13   0.56      t
22   0.19   0.44   0.26   0.11      s
23   0.36   0.31   0.30   0.04      v
Binding TFs: UP00501A (T-box)
Binding Sites: AAGTGTGA
AGGTGCGA
AGGTGTCA
AGGTGTCG
AGGTGTGA
AGGTGTTA
AGTGTGAA
GGGTGTGA
GGTGCGAA
GGTGTGAA
GTGTGAAA
GTGTGAAC
AACACCTC
ACACCTCC
ACACCTCG
AGGTGCTA
AGGTGTTG
CACACCTC
CTCACACC
GACACCTA
			
Publications: Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular evolution of DNA-binding preference of a Tbrain transcription factor provides a mechanism for modifying gene regulatory networks. Mol Biol Evol 31:2672-88 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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