DNA Binding Site

Accessions: ACACCTCG (UniPROBE 20160601), UN0808.1.14 (JASPAR 2024)
Organisms: Patiria miniata, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: ACACCTCG
Type: Heterodimer
Binding TFs: P17542 (Helix-loop-helix DNA-binding domain)
UP00501A / UP00501B (T-box)
P17542
Binding Motifs: UP00501A_1 / UP00501A_2 yskctrrAGGTGTGAAywwamst
UP00501A_3 / UP00501A_4 mrwmhsCsAGGTGACAtawstsv
UP00501B_1 / UP00501B_2 smsrsmrAGGTGYGAAmtwrdw
UP00501B_3 / UP00501B_4 whyccgkAGGTGwygsymshcs
UN0808.1 GCACCTGg
Publications: Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular evolution of DNA-binding preference of a Tbrain transcription factor provides a mechanism for modifying gene regulatory networks. Mol Biol Evol 31:2672-88 (2014). [Pubmed]

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