DNA Binding Motif

						

			
Accessions: 1hdd_CD (3D-footprint 20231221)

			
Names: PROTEIN (ENGRAILED HOMEODOMAIN)
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS
Length: 12
Consensus: TAnnnTnaTTAC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02     80      6      5      5      A
03     24     24     24     24      n
04     24     24     24     24      n
05     24     24     24     24      n
06      0      0      0     96      T
07     24     24     24     24      n
08     65      5     10     16      a
09      0      0      0     96      T
10      5      5      5     81      T
11     85      0      6      5      A
12      5     81      5      5      C
Binding TFs: 1hdd_C / 1hdd_D (Homeobox domain)
Binding Sites: 1hdd_A
1hdd_B
			
Publications: Kissinger C. R., Liu B., Martin-Blanco E., Kornberg T. B., Pabo C. O. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions. Cell 63:579-590 (1990). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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