DNA Binding Site

Accessions: 1hdd_A (3D-footprint 20231221), 3hdd_C (3D-footprint 20231221)
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 20
Sequence: TTTGCCATGTAATTACCTAA
Type: Heterodimer
Binding TFs: 1hdd_D (Homeobox domain)
3hdd_B (Homeobox domain)
Binding Motifs: 1hdd_CD TAnnnTnaTTAC
3hdd_AB GTAATAACnTTA
Publications: Kissinger C. R., Liu B., Martin-Blanco E., Kornberg T. B., Pabo C. O. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions. Cell 63:579-590 (1990). [Pubmed]

Fraenkel E, Rould M.A, Chambers K.A, Pabo C.O. Engrailed homeodomain-DNA complex at 2.2 A resolution: a detailed view of the interface and comparison with other engrailed structures. Journal of molecular biology 284:351-61 (1998). [Pubmed]

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