DNA Binding Motif

						

			
Accessions: MYBL1_MAX_2_3 (HumanTF2 1.0)

			
Names: MYBL1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: yAACsgymgwvgcrrrsCACGTG
Weblogo: 
PSSM: P0      A      C      G      T
01     62    161     15    224      y
02    385      0     25     11      A
03    385     12     24     22      A
04     11    385     16      8      C
05     52    281    385    127      s
06    145     26    385    127      g
07     69    105     16    195      y
08    123    144     24     94      m
09     68     93    159     65      g
10    110     79     77    118      w
11     99    105     98     83      v
12     77     87    133     88      g
13     89    137     91     68      c
14    111     74    127     73      r
15    108     65    161     51      r
16    104     74    119     88      r
17     54    132    139     60      s
18      1    385      5      6      C
19    385      2     24      0      A
20      1    385      4     19      C
21     30      7    385      3      G
22      2      9      0    385      T
23      0      6    385     18      G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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