DNA Binding Motif

Accessions: MYBL1_MAX_2 (HumanTF2 1.0)
Names: MYBL1_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: yAACskhhryvtggagCACGTG
Weblogo:
PSSM: P0 A C G T
01 87 203 54 300 y
02 504 3 26 14 A
03 504 21 18 16 A
04 24 504 15 0 C
05 45 404 504 192 s
06 144 93 504 248 k
07 132 155 39 178 h
08 146 147 53 157 h
09 151 101 165 87 r
10 98 164 93 148 y
11 134 136 135 99 v
12 105 125 108 166 t
13 125 117 168 94 g
14 94 87 234 89 g
15 158 104 123 119 a
16 102 114 201 87 g
17 2 504 0 3 C
18 504 8 29 13 A
19 2 504 8 40 C
20 16 2 504 3 G
21 8 12 6 504 T
22 3 3 504 20 G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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