Transcription Factor
Accessions: | 3zql_B (3D-footprint 20231221), 3zql_D (3D-footprint 20231221) |
Names: | PUTATIVE REPRESSOR SIMREG2, Q9AMH9_STRAT, Sim16 |
Organisms: | Streptomyces antibioticus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q9AMH9 |
Length: | 226 |
Pfam Domains: | 16-60 Bacterial regulatory proteins, tetR family 73-223 Tetracyclin repressor, C-terminal all-alpha domain |
Sequence: (in bold interface residues) | 1 VSIWMHPEPTLSRDQIVRAAVKVADTEGVEAASMRRVAAELGAGTMSLYYYVPTKEDLVE 60 61 LMVDEVIGETRLPDRPGPDWRAALTLAANEKRALWLRHPWLATAWRNGHPVWGPNSLRQQ 120 121 EFVLGTLGVFDLQVDELLSLIGLYNGYVESFVRNEVGWLEEARRTKVDMREWMRRSGPYA 180 181 QQLVDSGEYPMFARVLAETVAPHMGPDQRFRSGLERLLDSIGASLD |
Interface Residues: | 34, 35, 44, 45, 46, 47, 49, 50, 154 |
3D-footprint Homologues: | 5gpc_B, 6gy3_A, 5haw_A, 5yej_B, 3zql_B, 5fmp_B, 4gck_A, 1qpi_A, 4pxi_B, 2yvh_A, 7amn_A, 6en8_C, 7jnp_A, 6wpa_A, 5cl8_A |
Binding Motifs: | 3zql_AB TCGTACGnCGTACAA 3zql_B TTCGTACG 3zql_CD TTGTACGnCGTAcGA |
Binding Sites: | 3zql_E / 3zql_G 3zql_F / 3zql_H |
Publications: | Le T.B, Schumacher M.A, Lawson D.M, Brennan R.G, Buttner M.J. The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. Nucleic acids research 39:9433-47 (2011). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.