DNA Binding Motif

						

			
Accessions: 3zql_CD (3D-footprint 20231221)

			
Names: PUTATIVE REPRESSOR SIMREG2
Organisms: Streptomyces antibioticus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: DNA-bound form of TetR-like repressor SimR
Length: 15
Consensus: TTGTACGnCGTAcGA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      3     19      0     74      T
03      0      0     96      0      G
04      3      1      3     89      T
05     96      0      0      0      A
06      0     96      0      0      C
07      0      4     89      3      G
08     24     24     24     24      n
09      0     92      4      0      C
10      0      0     96      0      G
11      0      0      0     96      T
12     74      1     18      3      A
13     20     49     12     15      c
14      0     18     74      4      G
15     92      0      1      3      A
Type: Heterodimer
Binding TFs: 3zql_C (Bacterial regulatory proteins, tetR family, Tetracyclin repressor, C-terminal all-alpha domain)
3zql_D (Bacterial regulatory proteins, tetR family, Tetracyclin repressor, C-terminal all-alpha domain)
Binding Sites: 3zql_G
3zql_H
			
Publications: Le T.B, Schumacher M.A, Lawson D.M, Brennan R.G, Buttner M.J. The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. Nucleic acids research 39:9433-47 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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