Transcription Factor

Accessions: Rara_DBD (HumanTF 1.0)
Names: PML-RARA-regulated adapter molecule 1, PRAM_MOUSE, PRAM-1, Rara
Organisms: Mus musculus
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q6BCL1
Notes: Ensembl ID: ENSMUSG00000037992; DNA-binding domain sequence; TF family: Nuclear_Receptor; Clone source: Hughes lab.
Length: 104
Pfam Domains: 18-86 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 EIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKN 60
61 CIINKVTRNRCQYCRLQKCFDVGMSKESVRNDRKKKKKEAPKPE
Interface Residues: 27, 28, 30, 31, 37, 38, 39, 40, 41, 43, 44, 45, 48, 50, 54, 69, 73, 75, 77, 91, 93, 95, 98
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2nll_B, 1lat_A, 2ff0_A, 1dsz_A, 8hbm_B, 4umm_E, 3cbb_A, 7xv6_B, 4iqr_B, 2han_A, 1hcq_E, 7xvn_C, 2han_B, 1kb2_B, 2a66_A, 8cef_H, 5krb_G, 4yhx_A, 5cbz_E, 4hn5_B, 5e69_A, 8rm6_A, 3g6t_A, 1r4i_A, 5emc_A, 7prw_B, 5cbx_B, 4tnt_B
Binding Motifs: Rara_DBD_1 AAAGGTCAhsrrAGGTCA
Rara_DBD_2 AGGTCAmbyAAAGGTCA
Rara_DBD_3 rAGGTCAAAAGGTCA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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