Transcription Factor

Accessions: UP00198A (UniPROBE 20160601)
Names: Cphx, cytoplasmic polyadenylated homeobox, Homeobox protein ESO1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q8BX39
Description: cytoplasmic polyadenylated homeobox
Length: 93
Pfam Domains: 18-70 Homeobox domain
38-70 Homeobox KN domain
Sequence:
(in bold interface residues)
1 TKDNRSKARKRYGSRNSKPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVI 60
61 DNWFQNKRARLAPELKSKISAMRRMRRCQDYMR
Interface Residues: 15, 17, 18, 19, 20, 21, 22, 58, 61, 62, 65, 66, 69, 70
3D-footprint Homologues: 3cmy_A, 2h1k_B, 3d1n_M, 1zq3_P, 2lkx_A, 6m3d_C, 2ld5_A, 4cyc_A, 1ig7_A, 5flv_I, 1b72_A, 3a01_E, 1jgg_B, 5hod_A, 3lnq_A, 1puf_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1fjl_B, 4xrs_G, 2hos_A, 7psx_B, 1k61_B, 1le8_B, 1mnm_C, 2xsd_C, 7q3o_C, 7xrc_C, 5zfz_A, 6fqp_B, 3l1p_A, 5zjt_E, 4qtr_D, 6fqq_E, 1du0_A, 6a8r_A, 4xrm_B, 1puf_B, 8g87_X, 6es3_K
Binding Motifs: UP00198A_1 rTGATssmATCAaw
Binding Sites: AATCAATC
ACCAATCA
ATCAATCA
ATGATTGA
ATGATTGG
ATTGATTG
CAATCAAA
CAATCAAC
CAATCAAG
CAATCATA
CCAATCAA
CCAATCAC
CCAATCAG
CCCAATCA
GCCAATCA
GTCAATCA
GTGATTGA
TCAATCAA
TCCAATCA
TGATTGAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.