DNA Binding Motif

Accessions: UP00198A_1 (UniPROBE 20160601)
Names: Cphx, cytoplasmic polyadenylated homeobox, Homeobox protein ESO1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: rTGATssmATCAaw
Weblogo:
PSSM: P0 A C G T
01 0.34 0.18 0.26 0.22 r
02 0.03 0 0 0.96 T
03 0.04 0.02 0.93 0.01 G
04 0.98 0.01 0.01 0.01 A
05 0.04 0 0.06 0.90 T
06 0.10 0.37 0.29 0.24 s
07 0.22 0.28 0.35 0.15 s
08 0.54 0.34 0.08 0.04 m
09 0.95 0.03 0.01 0.01 A
10 0.01 0.01 0 0.99 T
11 0 0.97 0 0.02 C
12 0.95 0.01 0.01 0.03 A
13 0.61 0.14 0.15 0.10 a
14 0.36 0.21 0.10 0.33 w
Binding TFs: UP00198A (Homeobox domain, Homeobox KN domain)
Binding Sites: AATCAATC
ACCAATCA
ATCAATCA
ATGATTGA
ATGATTGG
ATTGATTG
CAATCAAA
CAATCAAC
CAATCAAG
CAATCATA
CCAATCAA
CCAATCAC
CCAATCAG
CCCAATCA
GCCAATCA
GTCAATCA
GTGATTGA
TCAATCAA
TCCAATCA
TGATTGAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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