Transcription Factor

Accessions: UP00315A (UniPROBE 20160601)
Names: Hal9, Halotolerance protein 9, O0938, YOL089C
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q12180
Description: Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decrease...
Length: 145
Pfam Domains: 51-88 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 NVAYPNTIYSPTEHQSQFQTQQNRDISTMMEHTNSNDMSGSGKNLKKRVSKACDHCRKRK 60
61 IRCDEVDQQTKKCSNCIKFQLPCTFKHRDEILKKKRKLEIKHHATPGESLQTSNSISNPV 120
121 ASSSVPNSGRFELLNGNSPLESNII
Interface Residues: 46, 47, 57, 59, 60, 61, 62, 78, 79
3D-footprint Homologues: 1f5e_P, 1pyi_A, 2er8_C, 1hwt_C, 1d66_B, 3coq_A, 7uik_T
Binding Motifs: UP00315A_1 TCCGnnnnnnnnnsCGGA
Binding Sites: AACGGAAA
AACGGAAC
ATCCGGAT
ATTCCGCG
CAACGGAA
CCGCGGAA
CGACGGAA
CGGATCCG
GACGGAAA
GAGCGGAA
GCGGAACA
GCGGAACC
GGCGGAAC
GTTCCGGA
TCCGCGGA
TTCCGGAA
ACGGAAAC
AGTTCCGC
CGCGGAAC
GACGGAAC
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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