Transcription Factor
| Accessions: | 4hn6_A (3D-footprint 20231221), 4hn6_B (3D-footprint 20231221) |
| Names: | GCR_HUMAN, Glucocorticoid receptor, GR, Nuclear receptor subfamily 3 group C member 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P04150 |
| Length: | 72 |
| Pfam Domains: | 1-69 Zinc finger, C4 type (two domains) |
| Sequence: (in bold interface residues) | 1 KLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGDNRCIIDKIRRKNCPACRY 60 61 RKCLQAGMNLEA |
| Interface Residues: | 11, 12, 14, 15, 21, 22, 24, 25, 28, 29, 53 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B |
| Binding Motifs: | 4hn6_AB CTcTnCcnnnnGCG |
| Binding Sites: | 4hn6_C 4hn6_D |
| Publications: | Hudson W.H, Youn C, Ortlund E.A. The structural basis of direct glucocorticoid-mediated transrepression. Nature structural & molecular biology 20:53-8 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.