Transcription Factor

						

			
Accessions: FOXC1_DBD (HumanTF 1.0)

			
Names: A3KPE3_HUMAN, FOXC1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: A3KPE3
Notes: Ensembl ID: ENSG00000054598; DNA-binding domain sequence; TF family: Forkhead; Clone source: Gene synthesis
Length: 130
Pfam Domains:    19-114 Fork head domain
Sequence: 
(in bold interface residues)		   1 MARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNK   60
  61 QGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDA  120
 121 VKDKEEKDRL
Interface Residues: 59, 62, 64, 65, 66, 68, 69, 70, 72, 73, 82, 89, 114
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3qrf_G
Binding Motifs: FOXC1_DBD_1 AarTAAAyAAAcA
FOXC1_DBD_2 wrtmAATATTkAyw
FOXC1_DBD_3 wAwRTMAAyAw
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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