Transcription Factor

Accessions: 2v2t_A (3D-footprint 20231221)
Names: RELB_MOUSE, TRANSCRIPTION FACTOR RELB
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q04863
Length: 279
Pfam Domains: 6-174 Rel homology domain (RHD)
Sequence:
(in bold interface residues)
1 CPRPYLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTQPAIELRDCGGLREVEVT 60
61 ACLVWKDWPHRVHPHSLVGKDCTDGVCRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIER 120
121 KIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGHLHRMDPILSEPVYDKKSTNTS 180
181 ELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSTASWEGRADFSQADVHRQIAIVF 240
241 KTPPYEDLEISEPVTVNVFLQRLTDGVCSEPLPFTYLPR
Interface Residues: 18, 20, 21, 23, 24, 26, 27, 28, 175, 177, 206, 213, 234
3D-footprint Homologues: 2o61_A, 1gji_A, 2ram_A, 1imh_C, 1nfk_A, 7cli_B, 1a3q_A, 3kqh_B
Binding Motifs: 2v2t_A GGgAnt
2v2t_AB GGkAAnTcCC
Binding Sites: 2v2t_C / 2v2t_D
Publications: Moorthy A.K, Huang D.B, Wang V.Y, Vu D, Ghosh G. X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. Journal of molecular biology 373:723-34 (2007). [Pubmed]
Related annotations: PaperBLAST

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