DNA Binding Site

Accessions: 1nfk_C (3D-footprint 20231221), 1nfk_D (3D-footprint 20231221), 2v2t_C (3D-footprint 20231221), 2v2t_D (3D-footprint 20231221)
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 10
Sequence: GGGAATTCCC
Type: Heterodimer
Binding TFs: 1nfk_A / 1nfk_B (Rel homology domain (RHD))
2v2t_A (Rel homology domain (RHD))
2v2t_B (Rel homology domain (RHD))
Binding Motifs: 1nfk_A kCCC
1nfk_AB GGGAatTCCC
2v2t_A GGgAnt
2v2t_AB GGkAAnTcCC
Publications: Ghosh G., van Duyne G., Ghosh S., Sigler P. B. Structure of NF-kappaB p50 homodimer bound to a kappaB site. Nature 373:303-310 (1995). [Pubmed]

Moorthy A.K, Huang D.B, Wang V.Y, Vu D, Ghosh G. X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. Journal of molecular biology 373:723-34 (2007). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.