Transcription Factor
Accessions: | UP00317A (UniPROBE 20160601) |
Names: | Hypothetical 43.1 kDa protein in GAL83-YPT8 intergenic region, Mig3, YER028C |
Organisms: | Saccharomyces cerevisiae |
Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
Uniprot: | P39943 |
Description: | Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, a... |
Length: | 118 |
Pfam Domains: | 16-38 C2H2-type zinc finger 32-57 Zinc-finger double domain 44-68 Zinc finger, C2H2 type 44-68 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 NYLRDRFPPDNDQRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDE 60 61 LKRHLRTHTKGVQRRRIKSKGSRKTVVNTATAAPTTFNENTGVSLTGIGQSKVPPILI |
Interface Residues: | 4, 5, 26, 27, 28, 29, 30, 32, 33, 35, 36, 39, 56, 57, 58, 59, 60, 63, 67, 83, 84, 85, 86, 88, 89, 90, 91 |
3D-footprint Homologues: | 2lt7_A, 7y3l_A, 2kmk_A, 8cuc_F, 8ssu_A, 8gn3_A, 7n5w_A, 5v3j_F, 8h9h_G, 7txc_E, 7ysf_A, 1ubd_C, 6u9q_A, 2drp_D, 1tf3_A, 7y3m_I, 1tf6_A, 6e94_A, 8ssq_A, 7w1m_H, 2jpa_A, 2gli_A |
Binding Motifs: | UP00317A_1 acryrytACCCCGCAwwtwrk |
Binding Sites: | AACCCCGC ACCCCACA ACCCCGCA ACCCCGCG ACGCGGGG ATGCGGGG ATGTGGGG CACCCCGC CCCCACAA CCCCACAC CCCCCACA CCCCCGCA CCCCGCAA CCCCGCAC CCCCGCAG GCCCCGCA GCGGGGAA GCGGGGGA GCGGGGTA TCCCCGCA |
Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
Related annotations: | PaperBLAST |
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