Transcription Factor
Accessions: | 3oqm_A (3D-footprint 20231221), 3oqm_C (3D-footprint 20231221), 3oqn_A (3D-footprint 20231221), 3oqn_C (3D-footprint 20231221), 3oqo_C (3D-footprint 20231221) |
Names: | Catabolite control protein A, CCPA_BACSU, Glucose-resistance amylase regulator |
Organisms: | Bacillus subtilis, strain 168 |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P25144 |
Length: | 332 |
Pfam Domains: | 4-49 Bacterial regulatory proteins, lacI family 61-272 Periplasmic binding proteins and sugar binding domain of LacI family 63-312 Periplasmic binding protein domain 171-331 Periplasmic binding protein-like domain |
Sequence: (in bold interface residues) | 1 MNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT 60 61 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI 120 121 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI 180 181 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP 240 241 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV 300 301 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK |
Interface Residues: | 5, 6, 15, 16, 17, 18, 20, 21, 27, 28, 29, 52, 55, 56 |
3D-footprint Homologues: | 3oqm_C, 7ce1_D, 1efa_B, 1l1m_B, 1jft_A, 1zvv_A |
Binding Motifs: | 3oqm_AC TGTnnnCGTTatCA 3oqm_C GTTatCA 3oqn_AC TGTaaGCGntnACA 3oqn_C CGCTTTCA 3oqo_AC TGnraACGcnnaCA 3oqo_C cGCTttCA |
Binding Sites: | 3oqo_E 3oqo_B 3oqm_B 3oqm_E 3oqn_B 3oqn_E |
Publications: | Schumacher M.A, Sprehe M, Bartholomae M, Hillen W, Brennan R.G. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic acids research 39:2931-42 (2011). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.