Transcription Factor

						

			
Accessions: 3oqm_A (3D-footprint 20231221), 3oqm_C (3D-footprint 20231221), 3oqn_A (3D-footprint 20231221), 3oqn_C (3D-footprint 20231221), 3oqo_C (3D-footprint 20231221)

			
Names: Catabolite control protein A, CCPA_BACSU, Glucose-resistance amylase regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P25144
Length: 332
Pfam Domains:      4-49 Bacterial regulatory proteins, lacI family
   61-272 Periplasmic binding proteins and sugar binding domain of LacI family
   63-312 Periplasmic binding protein domain
  171-331 Periplasmic binding protein-like domain
Sequence: 
(in bold interface residues)		   1 MNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT   60
  61 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI  120
 121 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI  180
 181 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP  240
 241 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV  300
 301 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK
Interface Residues: 5, 6, 15, 16, 17, 18, 20, 21, 27, 28, 29, 52, 55, 56
3D-footprint Homologues: 7ce1_D, 1efa_B, 3oqm_C, 1l1m_B, 1jft_A, 1zvv_A
Binding Motifs: 3oqm_AC TGTnnnCGTTatCA
3oqm_C GTTatCA
3oqn_AC TGTaaGCGntnACA
3oqn_C CGCTTTCA
3oqo_AC TGnraACGcnnaCA
3oqo_C cGCTttCA
Binding Sites: 3oqo_E
3oqo_B
3oqm_B
3oqm_E
3oqn_B
3oqn_E
			
Publications: Schumacher M.A, Sprehe M, Bartholomae M, Hillen W, Brennan R.G. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic acids research 39:2931-42 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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