Transcription Factor

						

			
Accessions: 3oqm_A (3D-footprint 20231221), 3oqm_C (3D-footprint 20231221), 3oqn_A (3D-footprint 20231221), 3oqn_C (3D-footprint 20231221), 3oqo_C (3D-footprint 20231221)

			
Names: Catabolite control protein A, CCPA_BACSU, Glucose-resistance amylase regulator
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P25144
Length: 332
Pfam Domains:      4-49 Bacterial regulatory proteins, lacI family
   61-272 Periplasmic binding proteins and sugar binding domain of LacI family
   63-312 Periplasmic binding protein domain
  171-331 Periplasmic binding protein-like domain
Sequence: 
(in bold interface residues)		   1 MNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKT   60
  61 TTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGI  120
 121 VFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDI  180
 181 AFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP  240
 241 TAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAV  300
 301 AMRLLTKLMNKEPVEEHIVELPHRIELRKSTK
Interface Residues: 5, 6, 15, 16, 17, 18, 20, 21, 27, 28, 29, 52, 55, 56
3D-footprint Homologues: 3oqm_C, 7ce1_D, 1efa_B, 1l1m_B, 1jft_A, 1zvv_A
Binding Motifs: 3oqm_AC TGTnnnCGTTatCA
3oqm_C GTTatCA
3oqn_AC TGTaaGCGntnACA
3oqn_C CGCTTTCA
3oqo_AC TGnraACGcnnaCA
3oqo_C cGCTttCA
Binding Sites: 3oqo_E
3oqo_B
3oqm_B
3oqm_E
3oqn_B
3oqn_E
			
Publications: Schumacher M.A, Sprehe M, Bartholomae M, Hillen W, Brennan R.G. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic acids research 39:2931-42 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.