Transcription Factor

						

			
Accessions: HINFP1_full (HumanTF 1.0)

			
Names: HINFP1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Notes: Ensembl ID: ENSG00000172273; Full protein sequence; TF family: znfC2H2; Clone source: hORFeome
Length: 518
Pfam Domains:   186-210 Zinc-finger double domain
  229-251 C2H2-type zinc finger
  229-251 Zinc finger, C2H2 type
  255-275 C2H2-type zinc finger
  255-278 Zinc finger, C2H2 type
  269-295 Zinc-finger double domain
  345-368 C2H2-type zinc finger
  345-368 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MPPPGKVPRKENLWLQCEWGSCSFVCSTMEKFFEHVTQHLQQHLHGSGEEEEEEEEDDPL   60
  61 EEEFSCLWQECGFCSLDSSADLIRHVYFHCYHTKLKQWGLQALQSQADLGPCILDFQSRN  120
 121 VIPDIPDHFLCLWEHCENSFDNPEWFYRHVEAHSLCCEYEAVGKDNPVVLCGWKGCTCTF  180
 181 KDRSKLREHLRSHTQEKVVACPTCGGMFANNTKFLDHIRRQTSLDQQHFQCSHCSKRFAT  240
 241 ERLLRDHMRNHVNHYKCPLCDMTCPLPSSLRNHMRFRHSEDRPFKCDCCDYSCKNLIDLQ  300
 301 KHLDTHSEEPAYRCDFENCTFSARSLCSIKSHYRKVHEGDSEPRYKCHVCDKCFTRGNNL  360
 361 TVHLRKKHQFKWPSGHPRFRYKEHEDGYMRLQLVRYESVELTQQLLRQPQEGSGLGTSLN  420
 421 ESSLQGIILETVPGEPGRKEEEEEGKGSEGTALSASQDNPSSVIHVVNQTNAQGQQEIVY  480
 481 YVLSEAPGEPPPAPEPPSGGIMEKLQGIAEEPEIQMV*
Interface Residues: 145, 154, 155, 181, 182, 183, 184, 185, 188, 189, 209, 210, 211, 212, 213, 214, 215, 216, 217, 220, 239, 240, 241, 242, 243, 245, 246, 265, 266, 267, 268, 269, 271, 272, 276, 284, 293, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 305, 307, 322, 323, 324, 325, 326, 327, 328, 329, 330, 331, 332, 333, 335, 355, 356, 357, 358, 359, 362
3D-footprint Homologues: 6a57_A, 6jnm_A, 8cuc_F, 4x9j_A, 2gli_A, 7n5w_A, 1g2f_F, 5kl3_A, 1llm_D, 4m9v_C, 8h9h_G, 8ssq_A, 6e94_A, 7y3m_I, 1ubd_C, 6ml4_A, 7w1m_H, 5k5l_F, 5yel_A, 1f2i_J, 2wbs_A, 5ei9_F, 7txc_E, 3uk3_C, 5v3j_F, 7y3l_A, 6u9q_A, 8ssu_A, 5kkq_D, 8gn3_A, 7ysf_A, 2kmk_A, 6blw_A, 5yj3_D, 5k5i_A, 2lt7_A, 1tf3_A, 1tf6_A, 2jpa_A, 2drp_D
Binding Motifs: HINFP1_full_1 carCGTCCGCgk
HINFP1_full_2 GCGGACGyysCArCGTCCGC
HINFP1_full_3 GCGGACSttsarCGTCCGC
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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