Transcription Factor
| Accessions: | UP00001A (UniPROBE 20160601) |
| Names: | E2F transcription factor 2, E2F-2, E2F2, Transcription factor E2F2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P56931 |
| Description: | E2F transcription factor 2 |
| Length: | 96 |
| Pfam Domains: | 16-81 E2F/DP family winged-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 GLPSPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDIT 60 61 NVLEGIQLIRKKSKNNIQWVGRELFEDPTRPSRQQQ |
| Interface Residues: | 16, 52, 53, 54, 55, 57 |
| 3D-footprint Homologues: | 1cf7_A, 4yo2_A, 1cf7_B |
| Binding Motifs: | UP00001A_1 rwwArgGCGCGCsaw UP00001A_2 hsywyGGCGCCAaavks |
| Binding Sites: | ACGCGCGC AGCGCGCG AGGCGCGC ATGGCGCC ATGGCGCG CCCGCGCG CGCGCCAA CGCGCGCC CGCGCGCG CGGCGCCA GCGCCAAA GCGCCATA GCGCGCAC GCGCGCCA GCGCGCGC GGCGCCAA GGCGCGCA GGCGCGCC GGGCGCCA TGGCGCCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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