Transcription Factor
| Accessions: | UP00472A (UniPROBE 20160601) |
| Names: | Vhr2, VHt1 Regulator |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | VHt1 Regulator : Non-essential nuclear protein; null mutation has global effects on transcription |
| Length: | 505 |
| Pfam Domains: | 20-112 Transcription factor Vhr1 |
| Sequence: (in bold interface residues) | 1 MIDDTENSKIHLEGSHKTGKYTGYGTTHKIRAQLNFNDEKKWKKFSSRRLELIDSFGLSQ 60 61 HKASEQDDNIRQIATILRSEFEYPDTFSAEFEKLVTAAVQSVRRNRKRSKKKLLDSKKKI 120 121 ARGKVQKIPLSPPSSSNMGSCSASNASSSDEEASVKEEPAEHALPSLNTITSQKLLPYPN 180 181 GRTLPPVPTQVRSLLKKNASLLRDPSAPYAHGGDEKLQKFDIEDQPLESEQEYDFIAKSI 240 241 IVEIVNNAIPLPEQIQRDKFIRPNLTKKKGCQSKVVISNNLRKLILSKIHNSRTCLEMSK 300 301 DERNLDSFANLETLGKNSLMASISLVVENSFSHLPSSTKQYLTERLSSIEFLTILSQRLF 360 361 MPATRQLFADLSQEKIQVRVLNLILGSLVKDYGFDASLAPINEIIYHMTLHQYPLVCSNK 420 421 QSNPMRPHSTSEVLSAHSSTKDASTPGKEEPRVTRSSTSADSTIITLPSIEVPNTYDDDR 480 481 LKMLSAISLQIENSTFSKPFSTISK |
| Interface Residues: | 48, 60 |
| 3D-footprint Homologues: | 2imw_P |
| Binding Motifs: | UP00472A_1 / UP00472A_2 tdhyrgdGATGACTCAytcahwr UP00472A_3 ATGACTwCacgC |
| Binding Sites: | GTGACTCA ATGACTAA ATGACTCA ATGAGTCA CATGACTC CTGACTCA CTGAGTCA GAGTCACA GAGTCACC GAGTCATA GAGTCATC GTGAGTCA TGACTCAA AATGACTC AGAGTCAT AGTCATCG ATGACTAC ATGACTCC CATGACTA GATGACTA |
| Publications: | Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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