Transcription Factor

Accessions: 5w43_B (3D-footprint 20231221)
Names: Capsular synthesis regulator component B, RCSB_ECOLI, Transcriptional regulatory protein RcsB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 194
Pfam Domains: 5-119 Response regulator receiver domain
130-180 Sigma-70, region 4
136-191 Bacterial regulatory proteins, luxR family
Sequence:
(in bold interface residues)
1 NNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPG 60
61 DKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALA 120
121 ALQKPESVSRLLEKIKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKL 180
181 GVENDIALLNYLSS
Interface Residues: 90, 91, 92, 94, 95, 116, 165, 166, 167, 168, 170, 171, 172, 174
3D-footprint Homologues: 3zpl_B, 7ve5_B, 5w43_B, 1zlk_A, 6ide_A, 4wuh_B
Binding Motifs: 5w43_AB taGGAannmTCTtA
5w43_B taAGA
Binding Sites: 5w43_E
5w43_F
Publications: Filippova EV, Zemaitaitis B, Aung T, Wolfe AJ, Anderson WF. Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB. MBio : (2018). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.