Transcription Factor
| Accessions: | UP00028A (UniPROBE 20160601) |
| Names: | AI505200, AP-2e, epsilon, Tcfap2e, transcription factor AP-2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q6VUP9 |
| Description: | transcription factor AP-2, epsilon |
| Length: | 238 |
| Pfam Domains: | 16-221 Transcription factor AP-2 |
| Sequence: (in bold interface residues) | 1 TLALSKDSLVGGISNPSEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGG 60 61 VLRRAKSKNGSRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETE 120 121 FPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPG 180 181 VQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLEKMFLSGAGGGHGESKASEK |
| Interface Residues: | 31, 65, 66, 131, 132, 136 |
| 3D-footprint Homologues: | 8j0k_B, 7r8i_A |
| Binding Motifs: | UP00028A_1 wwhSCCysrGGSraw UP00028A_2 wackkrAAAaAAwa |
| Binding Sites: | CCCCAGGC CCCCAGGG CCCCCGGG CCCCGAGG CCCCGGGC CCCCGGGG CCCGAGGC CCCGAGGG CCCTAAGG CCCTTAGG CCGCAGGC CCGGAGGC CCGGGGGC CCTCAGGC CCTCCGGC CCTCGGGC CCTGAGGC CCTGCGGC CCTGGGGC CCTTAGGC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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