Transcription Factor

						

			
Accessions: 4pu3_C (3D-footprint 20231221), 4pu3_D (3D-footprint 20231221)

			
Names: HIPB_SHEON, Toxin-antitoxin system antidote transcriptional repressor Xre family
Organisms: Shewanella oneidensis, strain MR-1
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8EIX4
Length: 71
Pfam Domains:     11-64 Helix-turn-helix domain
    14-65 Helix-turn-helix domain
    15-65 Helix-turn-helix
Sequence: 
(in bold interface residues)		   1 IMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDG   60
  61 LGIDIVSAGWY
Interface Residues: 26, 27, 36, 37, 38, 39, 41, 42, 48, 50
3D-footprint Homologues: 3cro_R, 4pu3_C, 5jub_B
Binding Motifs: 4pu3_ABCD AGGnTnnnnnnCTnA
4pu3_C AncCt
Binding Sites: 4pu3_P
4pu3_Q
			
Publications: Wen Y, Behiels E, Felix J, Elegheert J, Vergauwen B, Devreese B, Savvides S.N. The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic acids research 42:10134-47 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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