DNA Binding Motif

Accessions: 4pu3_ABCD (3D-footprint 20231221)
Names: Toxin-antitoxin system antidote transcriptional repressor Xre family
Organisms: Shewanella oneidensis, strain MR-1
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Shewanella oneidensis MR-1 Toxin Antitoxin System HipA, HipB and its operator DNA complex (space group P212121)
Length: 15
Consensus: AGGnTnnnnnnCTnA
Weblogo:
PSSM: P0 A C G T
01 73 7 9 7 A
02 0 0 96 0 G
03 9 7 73 7 G
04 24 24 24 24 n
05 0 0 0 96 T
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 7 75 7 7 C
13 9 7 7 73 T
14 24 24 24 24 n
15 96 0 0 0 A
Binding TFs: 4pu3_C / 4pu3_D (Helix-turn-helix, Helix-turn-helix domain, Helix-turn-helix domain)
Binding Sites: 4pu3_P
4pu3_Q
Publications: Wen Y, Behiels E, Felix J, Elegheert J, Vergauwen B, Devreese B, Savvides S.N. The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. Nucleic acids research 42:10134-47 (2014). [Pubmed]

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