Transcription Factor

Accessions: 3f27_D (3D-footprint 20231221)
Names: SOX17_MOUSE, Transcription factor SOX-17
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q61473
Length: 74
Pfam Domains: 1-69 HMG (high mobility group) box
2-64 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQ 60
61 HMQDHPNYKYRPRR
Interface Residues: 3, 6, 8, 9, 12, 16, 27, 28, 29, 32, 70, 74
3D-footprint Homologues: 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 3tq6_B, 1hry_A
Binding Motifs: 3f27_D ACAATa
Binding Sites: 3f27_A
3f27_B
Publications: Palasingam P, Jauch R, Ng C.K, Kolatkar P.R. The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms. Journal of molecular biology 388:619-30 (2009). [Pubmed]
Related annotations: PaperBLAST

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