Transcription Factor

						

			
Accessions: 1ais_A (3D-footprint 20231221), 1d3u_A (3D-footprint 20231221)

			
Names: BAP, Box A-binding protein, TATA sequence-binding protein, TATA-BINDING PROTEIN, TATA-box factor, TATA-box-binding protein, TBP_PYRWO
Organisms: Pyrococcus woesei
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P62001
Length: 181
Pfam Domains:      8-90 Transcription factor TFIID (or TATA-binding protein, TBP)
   98-181 Transcription factor TFIID (or TATA-binding protein, TBP)
Sequence: 
(in bold interface residues)		   1 MVDMSKVKLRIENIVASVDLFAQLDLEKVLDLCPNSKYNPEEFPGIICHLDDPKVALLIF   60
  61 SSGKLVVTGAKSVQDIERAVAKLAQKLKSIGVKFKRAPQIDVQNMVFSGDIGREFNLDVV  120
 121 ALTLPNCEYEPEQFPGVIYRVKEPKSVILLFSSGKIVCSGAKSEADAWEAVRKLLRELDK  180
 181 Y
Interface Residues: 13, 15, 43, 44, 58, 60, 66, 68, 103, 104, 106, 134, 135, 149, 151, 157, 159
3D-footprint Homologues: 7z7n_D, 1qna_B, 5n9g_G, 1ytb_A, 5oqj_O, 1ais_A, 4wzs_D, 6cnb_R, 1cdw_A, 5iy6_P
Binding Motifs: 1ais_A TTTTTAAA
1ais_AB TTTTTAAA
1d3u_A TTTAAATA
1d3u_AB TATTTAAAnnTTACT
Binding Sites: 1ais_C
1ais_E
1d3u_C
1d3u_D
			
Publications: Kosa P.F, Ghosh G, DeDecker B.S, Sigler P.B. The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box. Proceedings of the National Academy of Sciences of the United States of America 94:6042-7 (1997). [Pubmed]


Littlefield O, Korkhin Y, Sigler P.B. The structural basis for the oriented assembly of a TBP/TFB/promoter complex. Proceedings of the National Academy of Sciences of the United States of America 96:13668-73 (1999). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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