Transcription Factor

Accessions: UP00087A (UniPROBE 20160601)
Names: AA409384, Activating enhancer-binding protein 2 gamma, Ap-2.2, AP2-gamma, gamma, Tcfap2c, Tfap2c, transcription factor AP-2, Transcription factor AP-2 gamma
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q61312
Description: transcription factor AP-2, gamma: Mus musculus transcription factor AP-2, gamma, mRNA (cDNA clone MGC:5992 IMAGE:3592762), complete cds
Length: 239
Pfam Domains: 16-223 Transcription factor AP-2
Sequence:
(in bold interface residues)
1 LGLPCQKDLVGVVMNPSEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGG 60
61 VLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAE 120
121 FPSKAVADYLTRPHLGGRNEMATRKSMLLAAQQVCKEFTDLLHQDRTPNGNNRPAQVLEP 180
181 NIQNCLSHFSLITHGFGSQAICAAVSAVQNYIKEALIAIDKSYMNPGDQSPADSSKTME
Interface Residues: 31, 65, 66, 108
3D-footprint Homologues: 8j0k_B, 5l6l_D
Binding Motifs: UP00087A_1 wtysCCysrGGsraw
UP00087A_2 cyGCCcaagGGCwd
Binding Sites: CCCCAGGC
CCCCAGGG
CCCCCAGG
CCCCCGGG
CCCCGAGG
CCCCGGGC
CCCCGGGG
CCCGAGGG
CCCGCGGG
CCCGGGGC
CCCTCAGG
CCCTGAGG
CCGCAGGC
CCGGGGGC
CCTAAGGC
CCTCAGGC
CCTCCGGC
CCTCGGGC
CCTGAGGC
CCTGGGGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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