Transcription Factor

Accessions: UP00528A (UniPROBE 20160601)
Names: Forkhead homolog 16, Foxm1, Winged-helix transcription factor Trident
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 126
Pfam Domains: 16-100 Fork head domain
Sequence:
(in bold interface residues)
1 EPSGVSTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPG 60
61 WKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLEPGSPQSPEHLES 120
121 QQKRPN
Interface Residues: 60, 62, 63, 64, 66, 67, 68, 70, 71, 77, 84
3D-footprint Homologues: 7vox_H, 2hdc_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 3qrf_G
Binding Motifs: UP00528A_1 AwtkcawGATGCATCmTgmgwk
UP00528A_2 wrarcaymAwAACAAmwmhhmm
Binding Sites: AACAATGC
AGATGCAT
ATGCATCA
GATGCATC
AAAATGCA
AAGATGCA
AATGCATC
AGAATGCA
AGGATGCA
AGTGCATC
ATGATGCA
ATGCATCC
ATGCATTC
CAGGATGC
CATAACAA
GATGCACA
GCATCATA
GGATGCAC
GGGATGCA
GTGATGCA
Publications: Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.