Transcription Factor

Accessions: 4uno_A (3D-footprint 20231221)
Names: ETS TRANSLOCATION VARIANT 5, Ets-related protein ERM, ETV5_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P41161
Length: 95
Pfam Domains: 2-83 Ets-domain
Sequence:
(in bold interface residues)
1 SLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSL 60
61 RYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPD
Interface Residues: 42, 54, 55, 57, 58, 59, 61, 62, 76
3D-footprint Homologues: 6sjf_B, 7jsa_J, 4mhg_A, 2stt_A, 8ee9_F, 4uno_A, 3jtg_A, 1dux_F, 3zp5_A, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B
Binding Motifs: 4uno_A CGGa
Binding Sites: 4uno_B
4uno_C
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]
Related annotations: PaperBLAST

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