DNA Binding Site
| Accessions: | 1bc8_B (3D-footprint 20231221), 4uno_C (3D-footprint 20231221), 4uuv_X (3D-footprint 20231221), 5ybd_C (3D-footprint 20231221) |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 9 |
| Sequence: | ACTTCCGGT |
| Type: | Heterodimer |
| Binding TFs: | 1bc8_C (Ets-domain) 4uuv_S (Ets-domain) 4uuv_V (Ets-domain) 4uno_A (Ets-domain) 5ybd_A (Ets-domain) |
| Binding Motifs: | 5ybd_A tTCCg 1bc8_C CGGAa 4uno_A CGGa 4uuv_S ctTCCG 4uuv_SV CGGAAnTnnnCGGAnG |
| Publications: | Mo Y., Vaessen B., Johnston K., Marmorstein R. Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.. Mol. Cell 2:201-212 (1998). [Pubmed] Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed] Sharma R, Gangwar SP, Saxena AK. Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence. Acta Crystallogr F Struct Biol Commun : (2018). [Pubmed] |
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