Transcription Factor
| Accessions: | 1cqt_B (3D-footprint 20231221) |
| Names: | NF-A1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, OTF-1, PO2F1_HUMAN, POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P14859 |
| Length: | 129 |
| Pfam Domains: | 1-70 Pou domain - N-terminal to homeobox domain 71-126 Homeobox domain |
| Sequence: (in bold interface residues) | 1 DLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYNDFSQTTISRFEALNLSFKNMCKLKP 60 61 LLEKWLNDAERKKRTSIETNIRVALEKSFLENQKTSEEITMIADQLNMEKEVIRVWFCNR 120 121 RQKEKRINP |
| Interface Residues: | 23, 38, 39, 40, 41, 43, 44, 50, 54, 71, 72, 73, 74, 111, 112, 114, 115, 118, 119, 122, 123, 126 |
| 3D-footprint Homologues: | 7u0g_M, 3d1n_M, 3l1p_A, 7xrc_C, 1o4x_A, 8g87_X, 2xsd_C, 1e3o_C, 1au7_A, 1fjl_B, 2h1k_B, 1ig7_A, 2r5y_A, 6a8r_A, 1puf_A, 1zq3_P, 2lkx_A, 1nk2_P, 6m3d_C, 7q3o_C, 6es3_K, 1b72_A, 4xrs_G, 5zjt_E, 2hdd_A, 5hod_A, 3a01_E, 5jlw_D, 2ld5_A, 1le8_A, 3lnq_A, 3cmy_A, 3rkq_B, 1du0_A, 7psx_B, 5flv_I, 1jgg_B, 4cyc_A, 4qtr_D |
| Binding Motifs: | 1cqt_BJ TATTTGCATA |
| Binding Sites: | 1cqt_O 1cqt_P |
| Publications: | Chasman D, Cepek K, Sharp P.A, Pabo C.O. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes & development 13:2650-7 (1999). [Pubmed] |
| Related annotations: | PaperBLAST |
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