DNA Binding Site

Accessions: 1cqt_M (3D-footprint 20231221), 1cqt_O (3D-footprint 20231221), 1oct_A (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Type: Heterodimer
Binding TFs: 1cqt_A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1cqt_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1oct_C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Motifs: 1cqt_AI tATnCAAATA
Publications: Chasman D, Cepek K, Sharp P.A, Pabo C.O. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes & development 13:2650-7 (1999). [Pubmed]

Klemm J. D., Rould M. A., Aurora R., Herr W., Pabo C. O. Crytsal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77:21-32 (1994). [Pubmed]

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