DNA Binding Site

Accessions: 1cqt_M (3D-footprint 20231221), 1cqt_O (3D-footprint 20231221), 1oct_A (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Sequence: GTATGCAAATAAGG
Type: Heterodimer
Binding TFs: 1cqt_A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1cqt_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1oct_C (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Motifs: 1cqt_AI tATnCAAATA
1cqt_BJ TATTTGCATA
1oct_C TATGCAAA
Publications: Chasman D, Cepek K, Sharp P.A, Pabo C.O. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes & development 13:2650-7 (1999). [Pubmed]

Klemm J. D., Rould M. A., Aurora R., Herr W., Pabo C. O. Crytsal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules. Cell 77:21-32 (1994). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.