DNA Binding Motif

Accessions: 1cqt_BJ (3D-footprint 20231221)
Names: POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT
Length: 10
Consensus: TATTTGCATA
Weblogo:
PSSM: P0 A C G T
01 11 9 9 67 T
02 96 0 0 0 A
03 0 0 0 96 T
04 0 0 0 96 T
05 0 0 0 96 T
06 0 0 96 0 G
07 9 67 11 9 C
08 69 9 9 9 A
09 0 0 0 96 T
10 96 0 0 0 A
Binding TFs: 1cqt_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 1cqt_O
1cqt_P
Publications: Chasman D, Cepek K, Sharp P.A, Pabo C.O. Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. Genes & development 13:2650-7 (1999). [Pubmed]

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