Transcription Factor

						

			
Accessions: 2uzk_A (3D-footprint 20231221)

			
Names: AF6q21 protein, FORKHEAD BOX PROTEIN O3A, Forkhead in rhabdomyosarcoma-like 1, FOXO3_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O43524
Length: 97
Pfam Domains:      4-84 Fork head domain
Sequence: 
(in bold interface residues)		   1 MGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSL   60
  61 HSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVS
Interface Residues: 46, 49, 51, 52, 53, 55, 56, 57, 59, 60, 69, 74, 93
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3qrf_G
Binding Motifs: 2uzk_A tGtTTA
Binding Sites: 2uzk_B
2uzk_E
			
Publications: Tsai K. L., Sun Y. J., Huang C. Y., Yang J. Y., Hung M. C., Hsiao C. D. Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification.. Nucleic Acids Res. 35:6984-6994 (2007). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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