DNA Binding Motif

Accessions: 2uzk_A (3D-footprint 20231221)
Names: FORKHEAD BOX PROTEIN O3A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the human FOXO3a-DBD bound to DNA
Length: 6
Consensus: tGtTTA
Weblogo:
PSSM: P0 A C G T
01 13 13 14 56 t
02 7 7 74 8 G
03 19 19 19 39 t
04 0 0 0 96 T
05 6 6 6 78 T
06 88 2 2 4 A
Binding TFs: 2uzk_A (Fork head domain)
Binding Sites: 2uzk_B
2uzk_E
Publications: Tsai K. L., Sun Y. J., Huang C. Y., Yang J. Y., Hung M. C., Hsiao C. D. Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification.. Nucleic Acids Res. 35:6984-6994 (2007). [Pubmed]

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